Sometimes, the dysfunction comes from having had a UTI in the past, Stephanie Prendergast, CEO and co-founder of the Pelvic Health and Rehabilitation Center, tells Bustle. If the muscles around your bladder are too tight, this can lead to bladder or urethral pain and/or frequent urination. Pelvic floor dysfunction is improper positioning of your pelvic floor muscles, which surround your bladder, bowels, and reproductive organs. So, the presence of bacteria doesn't necessarily mean you have a UTI. Not all bacteria are problematic some are healthy bacteria that get into the sample from the vagina, and others are just part of the urinary microbiome. Jennifer Linehan, M.D, urologist and associate professor of urology and urologic oncology at the John Wayne Cancer Institute at Providence Saint John’s Health Center in Santa Monica, tells Bustle that another type of test called Next-Generation Sequencing (NGS) is even more accurate.Įven then, it may not always be clear what your results mean. If you think you might have a UTI that's not being detected, your doctor may be able to do a PCR laboratory test, Rice says. For instance, if someone has just urinated prior to leaving a sample and there is not a sufficient quantity of urine built up in the next voided sample, it is possible for a standard urine culture to report negative findings." A false negative can also occur if you've already taken antibiotics, so make sure not to do that. "Another possible reason for a false negative test (no bacteria grown) is that often, the test requires a certain number of bacteria to be grown in culture. "Standard urine cultures test for specific types of bacteria, but many women will have infections that are not able to be grown in these cultures," Rice says. One 2017 study in Clinical Microbiology and Infection found that one in five women with UTI symptoms had negative results on the standard tests, but almost all these women had UTIs according to the more sensitive quantitative polymerase chain reaction (qPCR) test. One possibility is that you really do have a UTI that's flying under the radar. How do you know if you actually have a UTI or something else, though? And what else could it be? Here are a few things UTI symptoms with negative test results could point toward - and what steps you and your doctor might need to take next. "I think that part of the increase in MDR organisms is the overuse of antibiotics for urinary symptoms that feel like a classic UTI but are not truly infectious in nature." In addition, there are healthy bacteria in your bladder that you don't want to eliminate if you can avoid it, she says. "In a world with increasing significant multi-drug resistant (MDR) bacteria, I am not a fan of antibiotics without culture positive results," she tells Bustle. Dana Rice, M.D., board-certified urologist and creator of the UTI Tracker app, cautions against taking antibiotics if you have no confirmed UTI, even if you have symptoms. Why does it matter, you ask? Well, it affects how you should go about treating it. Does this mean you have a UTI that's just not showing up on tests, or does it point toward a different health issue? It turns out those are both possibilities. Sometimes, people will have all the telltale signs of a UTI - a constant urge to pee even when nothing's in there, burning while peeing, bladder pain - but their urine cultures will come up negative. Over half of people with vaginas will get a urinary tract infection (UTI) at some point in their lives, but even more experience symptoms of one.
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